Hello,
I have seen this situation to be occurring after a maintenance on one of the fabric switches or after the switch is rebooted. forcing a LIP on the affected HBA should be able to bring back the connectivity without rebooting the Host
VMware KB: Forcing a Loop Initialization Primitive reset on Fibre Channel and Ethernet Adapters
http://www.van-lieshout.com/2010/01/how-to-force-a-login-on-a-qlogic-hba/
Thanks,
Avinash