I think this is more of a personal perference. It really depends on what you are trying to accomplish. I like the fact that my various clusters have some shared LUN's in common. That way I can easily move vm's between clusters all across the enterprise if needed. Maybe a solution would be to only configure certain datastores to which all 10 clusters would have access. Perhaps 10% of your total. That way you can be flexible, but you don't have to share out all 100 datastores out to all 10 clusters. When I do this I call them my swing LUNs and name them accordingly. That's just my two cents.
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