I'm having a thought on this as well. I have a pretty small environment ( 2 hosts, 1 shared storage and 1 SAN switch, vSphere essential plus, support up to 3 hosts ).
I had seek advise from a storage consultang on this matter and they suggest to configure multiple-initiator zoning since I have only one SAN switch. I'm not sure which one to follow since vmware come out with a best practice of using SIZoning. What would you suggest on my environment? Probably, we might add another SAN switch in near future.